Note: Once you start this operation, do not interrupt it before it’s completed. It does this by leveraging a locally stored archive to replace corrupted items with healthy equivalents. This utility is perfectly capable of functioning without an internet connection. A good way to start is to run a System File Checker scan. If this scenario is applicable, you should be able to fix the problem by running a couple of built-in utilities capable of fixing corrupted instances. One of the most common instances that will end up causing the ‘ Configuration Registry Database is Corrupt‘ error is some type of system corruption that ends up affecting your computer’s ability to launch applications signed by Microsoft.

If it’s still occurring, consider using System Restore to return your computer back to a healthy state.

In this case, repeat the procedure from a clean boot and see if the problem is resolved. 3rd Party App conflict – You might also see this error due to a conflict between native utilities like DISM or SFC and a 3rd party process.

If this doesn’t work, go for the nuclear option of resetting every OS component with a procedure like a clean install or repair install. In this case, see if you are able to fix the problem by running SFC and DISM scans.

System File Corruption – One of the most common instances that might cause this error is some type of system file corruption that ultimately affects the handling of applications signed by Microsoft Corp.

In this case, using the Online Repair option on Microsoft Office should allow you to fix the problem.

Corrupted Office installation – If a recent AV scan ended up quarantining some files or dependencies belonging to Microsoft Office, you’re most likely seeing this error due to some type of corruption rooted in the Registry.

Configuration registry database corrupt